C&en: Science & Technology - a Total Synthesis Detective Story

نویسندگان

  • Taotao Ling
  • Wenjun Tang
  • Goran Petrovic
  • Theocharis V. Koftis
  • K. C. NICOLAOU
  • Takeshi Yasumoto
  • Masayuki Satake
چکیده

The story starts in November 1995 with an incident of human food poisoning in the Netherlands following the consumption of blue mussels, Mytilus edulis, that had been harvested in Killary Harbour, Ireland. The symptoms--nausea, vomiting, severe diarrhea, and stomach cramps--were similar to diarrhetic shellfish poisoning (DSP). Levels of DSP toxins in the mussels, however, were found to be very low, so the involvement of a new marine toxin was suspected.

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تاریخ انتشار 2004